Sinai-Emory Multi-Institutional CIVIC (SEM CIVIC)

About

The Sinai-Emory Multi-Institutional CIVIC (SEM CIVIC) aims to develop improved seasonal and universal influenza virus vaccines that induce long-lasting protection against drifted seasonal, zoonotic, and future pandemic influenza viruses. This will be achieved through an iterative process of vaccine design, pre-clinical testing of candidates in animal models including mice, guinea pig, hamsters, ferrets, and non-human primates, clinical trials in collaboration with other CIVICs components, and detailed assessment of humoral and cellular immune responses in animals and humans. The Vaccine Center combines diverse expertise in vaccinology and translational vaccine development, molecular virology, immunology, including B cell and T cell immunity, antibody function and innate immunity, structural biology, epidemiology, and computational biology. Our team includes investigators with a strong background in influenza virus research, as well as investigators new to the field.

  • SEM CIVIC Homepage
Florian Krammer

Principal Investigator

PROFESSOR, MICROBIOLOGY

Icahn School of Medicine at Mount Sinai

Rafi Ahmed

co-Principal Investigator

PROFESSOR, MICROBIOLOGY AND IMMUNOLOGY,

Director, Emory Vaccine Center

Emory University

Investigators

Icahn School of Medicine at Mount Sinai

Emory University

La Jolla Institute for Immunology

PATH Center for Vaccine Innovation and Access

The Rockefeller University

The Scripps Research Institute

  • Ian Wilson, PhD, Professor and Chair, Department of Integrative Structural and Computational Biology
  • Andrew B. Ward, PhD, Professor, Department of Integrative Structural and Computational Biology

Stanford University

University of Chicago

University of Michigan

University of Minnesota

University of Wisconsin-Madison

Washington University School of Medicine 

The Wistar Institute

Yale University

  • Akiko Iwasaki, PhD, Professor, Departments of Immunology and Molecular, Cellular, and Developmental Biology

Other Key Personnel

Program Manager

  • Chiara Mariottini, PhD, Assistant Professor, Department of Microbiology, Icahn School of Medicine at Mount Sinai

Center Coordinator

  • Bindu Chadaga, Grants Manager, Department of Microbiology, Icahn School of Medicine at Mount Sinai

Data Manager

  • Changsu Dong, Data Manager, Icahn School of Medicine at Mount Sinai